Top Ten Defective Drugs and Drug-Induced Injuries in 2012
Each year, more and more drugs are approved for sale in the United States by the Food & Drug Administration. With each new approval, however, it seems that yet another drug falls under a cloud of suspicion due to safety concerns and product defects. Many scientists and public safety advocates have expressed concerns over the excessively fast pace for drug approvals and the very limited amount of data from safety studies that are reviewed prior to approval of a new pharmaceutical for marketing. Sadly, there are a number of drugs, both old and new, that are currently the subject of serious safety concerns and litigation:
- Pradaxa- acts as a blood “thinner” and is promoted to reduce the risk of stroke and blood clots in people with atrial fibrillation. Atrial fibrillation, affecting over two million Americans, occurs when the heart does not beat properly causing blood clots to form, increasing risk of a stroke. Studies have shown that Pradaxa is known to actually cause uncontrollable and internal bleeding in patients and has caused at least 260 deaths since 2010.
- Diabetes Drugs – Actos, the most popular insulin-sensitizer drug, has been linked to bladder cancer, even in patients who have only taken Actos for a year. There are also reports of macular edema caused by Actos. Actos is the third drug in this particular class, also known as thiazolidinediones, which have been associated with serious injuries and numerous patient deaths. The first insulin-sensitizer to be recalled was Rezulin, after it was linked to liver toxicity. The second dangerous diabetes drug was Avandia, and the use of Avandia has now been severely limited after years of patients dying or suffering heart attacks, strokes, or congestive heart failure caused by the medication.
- Osteoporosis Drugs – Fosamax, Boniva, Actonel, Alendronate, Didronel, Aredia, Zometa, and a number of other medications are included in the bisphosphonate class of drugs and have been widely prescribed for the treatment of osteoporosis, Paget’s disease, and bone metastases. In early 2010, patients were warned that long-term use of Fosamax and other drugs had been linked to the development of atypical femur fractures, where patients suffer traumatic breaks in their thigh bone or bones due to an internal weakening of the bone caused by long-term use of osteoporosis drugs. Bisphosphonates have also been linked to jaw osteonecrosis and arrhythmias, and there are ongoing studies to determine whether these same osteoporosis drugs also cause esophageal cancer.
- Multaq – This anti-arrhythmia drug has been tied to a number of serious health issues in recent months, including heart failure, torsade des pointes ventricular arrhythmias, stroke, liver failure, serious drug interactions, and death.
- Anti-Depressants – The SSRI (selective serotonin reuptake inhibitor) class of anti-depressants includes Prozac, Paxil, Celexa, Effexor, Lexapro, Pristiq, and Zoloft. These popular anti-depressants have been noted to cause a number of serious birth defects when ingested during the first trimester of a mother’s pregnancy. These birth defects include:
- Atrial/septal defects, abnormal formation of tissue that separates one chamber of the heart from the other
- Other cardiac (heart) defects and congenital malformations
- Persistent pulmonary hypertension (PPH), in which high pressure in the blood vessels of the lungs make it hard for newborn babies to breathe
- Autism spectrum disorder, neurological disorders resulting in complex developmental disabilities related to social interaction and communication skills
- Neural-tube defects (brain and spinal cord)
- Craniosynostosis (skull defects)
- Infant omphalocele (abdominal wall defects)
- Clubfoot (one or both feet turn downward and inward)
- Anal atresia (complete or partial closure of the anus)
- Cleft lip and cleft palate
- Limb defects (arms and/or legs)
- Premature births
If you or anyone you know has taken any of these listed drugs and is suffering from any of these conditions, don’t hesitate to give us a call 1-888-WE-MEAN-IT (888-936-3264). Our highly trained intake specialists will answer any questions you may have.